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This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology. .

Medicine. --- Cancer research. --- Human genetics. --- Molecular biology. --- Life sciences. --- Cell biology. --- Biomedicine. --- Cancer Research. --- Cell Biology. --- Human Genetics. --- Molecular Medicine. --- Life Sciences, general. --- Non-coding RNA. --- Colon (Anatomy) --- Cancer. --- Colon cancer --- Colorectal cancer --- fRNA --- Functional RNA --- ncRNA --- nmRNA --- Non-messenger RNA --- Non-translated RNA --- Noncoding RNA --- Nontranslated RNA --- Small non-messenger RNA --- Small RNA --- snmRNA --- sRNA --- Untranslated RNA --- RNA --- Oncology. --- Cytology. --- Biosciences --- Sciences, Life --- Science --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Genetics --- Heredity, Human --- Physical anthropology --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Tumors --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Medical genetics. --- Medicine --- Cancer Biology. --- Medical Genetics. --- Biomedical Research. --- Life Sciences. --- Research. --- Biological research --- Biomedical research --- Health Workforce --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Genetic disorders --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Genetic aspects

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Oncology --- personalized medicine --- precision oncology --- pediatric oncology --- trial models --- drug models --- personalized precision pediatric oncology --- clinical trial designs

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

personalized medicine --- precision oncology --- pediatric oncology --- trial models --- drug models --- personalized precision pediatric oncology --- clinical trial designs